The Silent Mutation

Phosphate: the Silent Challenge

Phosphorus (P) is one of the most vital elements for all living organisms which acts as aconstituent of essential biomolecules such as nucleic acids, phospholipids, and phosphosugars,and as a major contributor to almost all metabolic reactions including photosynthesis,respiration, and energy delivery. It is one of the most needed nutrients for plant growth anddevelopment. Despite high levels of...

silent mutation in kiss1 and kiss1r and unexplained infertility

Primary Malignant Lymphoma of Prostate with Silent MYD88 Mutation

We present a case of primary malignant lymphoma of the prostate in a 77-year-old Japanese man. Immunohistochemical examinations revealed the presence of a non-GCB subtype of DLBCL (CD10 (-), Bcl-6 (-), MUM1 (+)), and genetic analysis disclosed a lack of typical codon 206 or 265 missense mutation in MYD88, suggesting that the case was of type3 (non-GCB andnon-ABC), a subtype of DLBCL. Three cour...

the silent sinus syndrome

the silent sinus syndrome (sss) involves painless facial asymmetry and enophthalmos, which is theresult of chronic maxillary sinus atelectasis. in most cases, it is diagnosed clinically, however, usingthe characteristic imaging features including maxillary sinus outlet obstruction, sinus opacification,and sinus volume loss caused by inward retraction of the sinus walls. obstruction of the maxil...

circassians; the silent crisis

abstract circassians are one of the ethnic groups in the south-west of the caucasus who speak circassian language which is one of the branches of the north-east caucasus languages (ebrian-caucasian). this ethnic branch includes the caucasian ethnic abkhaz-adygian group, which are nowadays divided in three republics in the north caucasus kabardino-balkaria, karachay-cherkessia and adygeya. by us...